Milk, Soy Milk, Milk-Based Smoothies Calcium can interfere with the effectiveness of thyroid medication. Milk thistle can change the way that your body metabolizes certain drugs in the liver, triggering interactions with: High blood pressure occurs when the artery wall pressure rises above 120 systolic and 90 diastolic, which is measured in millimeters of mercury. Below is a short list of some other medications that are processed through the CYP3A4 enzyme. - Causes, Symptoms & Treatment, What Is Dysphagia? 30 July 2001.Related: PK and drug interactions. If gone unchecked, high blood pressure may damage the kidneys, blood vessels and the heart. The HCV Advocate says that the lipid-lowering drugs Lescol, Mevacor, Pravachol, Zocor and Baycol all have the potential to interact with milk thistle in this way. The material appearing on LIVESTRONG.COM is for educational use only. Of ALL the herbs and alternative medicines, it is regarded as the best one for protecting and helping the liver to heal itself. Herbal Health Technician: Profile of a Career in Herb Medicine. You will also learn about the interactions it can have with other medications, safety concerns, and contraindications. Top answers from doctors ... Certain blood pressure medications can cause dangerous rebound effects if … What is the Difference Between Blended Learning & Distance Learning? It is also used as a diuretic for increasing urine output, and for promoting the flow of breast milk in new mothers. Milk thistle seed might protect liver cells from toxic chemicals and drugs. Common interactions include fall among females and fatigue among males. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Allergy drugs-- such as fexofenadine (Allegra) Drugs for high cholesterol-- such as lovastatin (Mevacor, Altocor) Supplements that may interact with these medications include fish oil and St. John's wort. Herb-Drug Interactions Milk thistle is an inhibitor of cytochrome P-450 3A4 (CYP-450 3A4). Good luck. | {{course.flashcardSetCount}} ConsumerLab.com's answer explains. study Possible interactions include: 1. Milk thistle is a plant also known as Artichaut Sauvage, ... high blood pressure, high ... warnings, drug interactions, allergic reactions, or adverse effects. Create your account, Already registered? Milk thistle may interfere with many medications and increase them to dangerous levels because the same liver enzymes break down the herb. If you take any prescription medications, check with your healthcare provider before taking milk thistle. Metronidazole (Flagyl). Your research tells you that milk thistle is likely safe for most people, but that there is a chance of side effects, mostly related to the digestive system. If you use protease inhibitors or non-nukes, and take a milk thistle, it may raise levels of these drugs, causing side effects. You think it might be helpful for your gallbladder issues. Re: Milk Thistle Interactions with Blood Pressure Drugs? The study is created by eHealthMe based on reports of 236 people who take Lisinopril and Milk thistle from the FDA, and is updated regularly. The milk thistle I have is 1000mg. This can cause excess sedation, a lowering of blood pressure, physical depression, suppression of the lungs and cognitive impairment. - Definition, Types, Requirements & Risks, What is Chronic Gastritis? These are also enzymes in the body that break down medications, and taking milk thistle can increase the level of those drugs as well as their side effects. Copyright Policy Milk Thistle Protects Your Liver. An in vitro study has shown that Milk Thistle had interactions with several drugs, particularly some HIV drugs, due to it blocking an enzyme in the liver which controls a detoxification pathway. Taking milk thistle with diabetes drugs might cause additive effects. Food- Milk thistle leaves and flowers can be used in salads as a substitute for vegetables or greens like spinach. A salesperson approaches you and asks if they can interest you in an herbal medicine that can be used to treat many illnesses from liver disease to mushroom poisoning and can even be sprinkled on your salad! Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Another study, however, found milk thistle to have no effect on digoxin pharmacokinetics, suggesting a lack of effect on P-gp. This can cause excess sedation, a lowering of blood pressure, physical depression, suppression of the lungs and cognitive impairment. Although milk thistle helps reduce glucose levels in the blood, meaning that it may be beneficial for patients with diabetes, it is very important to understand that if medication for this … Cancer - Some early studies suggest that milk thistle may stop cancer cells from dividing and reduce blood supply to tumors. Milk thistle, as an inhibitor of this enzyme, blocks it from working as well and prevents or slows how well it can break down certain drugs. Milk Thistle Interactions With Blood Pressure Drugs Smell Your Does Make Urine both types of liver failure have similar symptoms which we’ll address here. When taking Invokana with a high blood pressure medication, your blood pressure may become too low. - Definition, Causes & Treatment, Quiz & Worksheet - The Female Reproductive Axis, Quiz & Worksheet - Male Reproduction Hormones, Quiz & Worksheet - Menses in the Uterine Cycle, Quiz & Worksheet - Phases of the Uterine Cycle, Quiz & Worksheet - Luteal Phase of the Ovarian Cycle, Science Experiments: Elementary & Middle School, Science Fair Projects: Elementary & Middle School, CPA Subtest IV - Regulation (REG): Study Guide & Practice, CPA Subtest III - Financial Accounting & Reporting (FAR): Study Guide & Practice, ANCC Family Nurse Practitioner: Study Guide & Practice, Pre-Civil War Sectional Conflict (1850-1861), Roles & Responsibilities of Teachers in Distance Learning. Milk thistle has been shown to have antioxidant and anti-inflammatory properties. History of hormone-related cancers (breast, uterine, prostate), or hormone-sensitive conditions (endometriosis, uterine fibroids) as milk thistle can act like estrogen and affect levels of hormones in the body. As far as I know there have never been any serious negative side effects attributable to Milk Thistle. Milk thistle may interact with other drugs. 2020 - Definition, Causes, Symptoms & Treatment, What Is Encopresis? Milk thistle can increase levels of some drugs and can also lower those levels. Milk thistle has many uses. Milk thistle can change the way that your body metabolizes certain drugs in the liver, triggering interactions with: 2014; 13: 347–391, Published online 2014 Apr 2. - Causes, Symptoms & Treatment, What Is Dumping Syndrome? - Definition & Types, Valerian Root: Side Effects & Drug Interactions, Ajuga Parviflora: Medicinal Uses & Chemical Constituents, Ajuga Reptans: Varieties & their Medicinal Uses, Milk Thistle: Dosage, Side Effects & Overdose Symptoms, Biological and Biomedical Milk thistle is an herb that has been used for 2,000 years, most commonly for the treatment of liver and gallbladder disorders. Ginger: Although Ginger does interact with many medications, particularly those related to blood clotting, it does not react with metoprolol. Answered by Dr. Anne Larson: No Interaction: These medicines do not interact with Milk Thistle… Kaitlin has taught nursing students and has a master's degree in nursing leaderhsip, as well as a bachelor's degree in English literature. * MILK THISTLE. Take milk thistle in capsule, extract or infusion form. eHealthMe makes it possible for everyone to run their own phase IV clinical trial. Taking milk thistle might decrease how well the body breaks down raloxifene (Evista) in the intestines. Milk thistle can increase levels of some drugs and can also lower those levels. Overview: Milk Thistle has been used for thousands of years. A warning about milk thistle (silymarin) and drug interactions. Check with your healthcare provider before taking Invokana with a blood pressure medication. Those who took silymarin also showed some weight loss and reduced diastolic blood pressure , but these effects were not significant. Blood pressure is defined as the pressure pushed against artery walls as a result of the heart pumping blood. Terms of Use 2. Privacy Policy For this reason, it has been shown to be useful (or potentially useful) in treating the following conditions: So, you bought some milk thistle from the mall salesperson. He or she should monitor your blood pressure carefully, and adjust the dosage of one or both medications … {{courseNav.course.mDynamicIntFields.lessonCount}} lessons Pregnancy or breastfeeding. You would probably think that they are at the very least stretching the truth, but it might surprise you to learn that there is such a medicine. Anyone can earn Supplements should contain 70 to 80 percent silymarin, which is what’s extracted from the seeds. However, determining the potential for clinically significant drug interactions with milk thistle products has been complicated by inconsistencies between in vitro and in vivo study results. Milk thistle or silymarin comes from the seeds of the plant it is named for and gets its name from the milky sap that comes out of the plant's leaves when they are broken. Milk thistle may interfere with the following medications, because both milk thistle and these medications are broken down by the same liver enzymes: Allergy drugs -- such as fexofenadine (Allegra) Drugs for high cholesterol -- such as lovastatin (Mevacor, Altocor) Select a subject to preview related courses: In doing your research into the safety of milk thistle you learn that the U.S. Food and Drug Administration (FDA) does not strictly regulate herbs and supplements. credit by exam that is accepted by over 1,500 colleges and universities. * MILK THISTLE. Diabetes medications are also used to lower blood sugar. and Use of this web site constitutes acceptance of the LIVESTRONG.COM used as a substitute for professional medical advice, Learn about supplement interactions with apixaban (Eliquis), rivaroxaban (Xarelto) and other blood thinner drugs in the direct factor Xa inhibitors class. The milk thistle I have is 1000mg. However, because so little information is available, it is not known which medications might interact with milk thistle or how exactly to handle these interactions. Milk thistle may also help patients with Hepatitis C. Mushroom Poisoning -Animal studies have found that milk thistle counteracts toxic effects of the ''death cap'' mushroom (. Medical Disclaimer: The information on this site is for your information only and is not a substitute for professional medical advice, To unlock this lesson you must be a Study.com Member. This document does not contain all possible interactions. This investigation will take approximately 8 weeks and involve 10 clinic visits. Get the unbiased info you need to find the right school. Milk thistle is sometimes used as a natural treatment for liver problems. Milk thistle may interfere with many medications and increase them to dangerous levels because the same liver enzymes break down the herb. McLelland studied communication and theater at St. Louis Community College. Log in here for access. You also discover that there are certain conditions that might be absolute contraindications to milk thistle due to the potential for harmful interactions. Cytochrome P450 2C9 (CYP2C9) substrates. Published February 24 2014. This excess of drugs could lead to uncomfortable or even dangerous side effects. Milk thistle compounds significantly improved markers for type 2 diabetes over placebo and over baseline measurements in patients. The University of Maryland Medical Center reports milk thistle is available in liquid extract, standardized dried extract in capsule form as well as a tincture. Secondly, a drug interaction study will be performed. Milk thistle may reduce your blood sugar, so it needs to be used with caution as it may trigger hypoglycemia (low blood sugar) in people on diabetes medications. Some cellular studies found that milk thistle may affect CYP enzymes in the liver that metabolize drugs; human studies suggest this effect is minor, but interactions are possible [ 29 ]. Milk thistle is often sold as an herbal supplement. https://www.statnews.com/2016/11/03/medications-food-drug-interactions Create an account to start this course today. MayoClinic.com states animal and laboratory research found milk thistle may be capable of lowering high cholesterol levels; however, further research is necessary to determine its true effectiveness. You should always be very cautious taking any medication with ginger tea. diagnosis or treatment. . Diabetes medications. Enrolling in a course lets you earn progress by passing quizzes and exams. This compound is actually comprised of three chemicals, known as silicristin, silibinin and silidianin. Basically will there be any bad side effects if I take blood pressure meds like atenolol and norvasc with milk thistle of course at different times. But before you take some, you decide to do some research on the interactions it may have with some of the medications you are currently taking. Common side effects may include: indigestion, bloating, gas, stomach pain; diarrhea; or nausea, loss of appetite. 's' : ''}}. The dose of your diabetes medication might need to be changed. and career path that can help you find the school that's right for you. Ask doctors free. Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage. ... No Interaction: These medicines do not interact with Milk Thistle. Copyright © The seeds of the milk thistle plant are commonly used to protect the liver from damage caused by hepatitis viruses as well as alcohol and other substances. Drug interactions are reported among people who take Lisinopril and Milk thistle. credit-by-exam regardless of age or education level. Examples of these drugs are some immunosuppressants, chemotherapeutic drugs, antifungals, antibiotics, many antidepressants and antianxiety drugs, blood thinners, allergy medications (such as Allegra), cholesterol medications, birth control, and caffeine. It is most well known as a superior herb for liver health. Services. Milk thistle has been used to treat disorders of the liver and gallbladder for at least 2,000 years. {{courseNav.course.topics.length}} chapters | Milk thistle is also a modulator for UGT (Uridine 5'-diphospho-glucuronosyltransferase) substrates. Although milk thistle helps reduce glucose levels in the blood, meaning that it may be beneficial for patients with diabetes, it is very important to understand that if medication for this condition is taken, this plant should not be taken without medical supervision. Diabetes because milk thistle can lower blood sugar and may affect dosing of other blood sugar medications. Many of those uses are based on tradition or untested theories. © copyright 2003-2020 Study.com. 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It also seems to have blood sugar-lowering, antioxidant, and anti-inflammatory effects. If you are experiencing serious medical symptoms, please see the, National Library of Medicine’s list of signs you need emergency medical attention, National Heart Lung and Blood Institute; What is High Blood Pressure? Below is a short list of some other medications that are processed through the CYP3A4 enzyme. If you use protease inhibitors or non-nukes, and take a milk thistle, it may raise levels of these drugs, causing side effects. All other trademarks and copyrights are the property of their respective owners. Milk Thistle (Silybum Marianum) Many drugs and environmental toxins are processed through the liver. Raloxifene ( Evista) Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider. Some people also call it Mary thistle and holy thistle. Research shows that the silymarin in milk thistle helps protect the … LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. USES: Milk thistle has been used for diabetes in combination with standard treatment. Life Brand Milk Thistle is standardized to 80% silymarin in a base of dandelion and turmeric, two botanicals that, combined with milk thistle, help maintain liver health. advertisements are served by third party advertising companies. Milk thistle may reduce your blood sugar, so it needs to be used with caution as it may trigger hypoglycemia (low blood sugar) in people on diabetes medications. The University of Maryland Medical Center states this herb should never be taken alongside antipsychotics, allergy medications, anti-anxiety drugs and high cholesterol medications. Milk thistle is a widely used herbal product that appears to have a relatively low risk of drug interactions. 10-19: Anaemia (lack of blood) Gastrointestinal haemorrhage (bleeding gastrointestinal tract) do these drugs interact with milk thistle?" Although milk thistle has been historically used to enhance fertility and improve the flow of breast milk, as there is not enough reliable medical research about safety. "what do you suggest if my father takes lamivudine and tenofovir for his liver. The seeds of the milk thistle plant are commonly used to protect the liver from damage caused by hepatitis viruses as well as alcohol and other substances. However decreasing your dog’s exposure to toxic drugs plants chemicals and other substances will help to protect him from it. This group of flavonoids is also known for their powerful antioxidant properties, which help protect the body from damage done by free radicals. Earn Transferable Credit & Get your Degree. Common interactions include fall among females and fatigue among males. All rights reserved. These include: Milk thistle, also known as silymarin, may be useful for treating many conditions, such as liver disease, mushroom poisoning, cancer, and even fertility. Silymarin, a chemical found in milk thistle, can decrease blood sugar levels. Many meds for people with AIDS, for example, are processed by this liver enzyme. While no scientific evidence exists to determine the entire effect milk thistle has on blood pressure, it may be possible this herb may indirectly lower blood pressure. Blood pressure is directly affected through dietary sources. Not sure what college you want to attend yet? Milk thistle should not be used in place of medication prescribed for you by your doctor. Take milk thistle in capsule, extract or infusion form. The result is high-than-normal levels of those drugs in the body. One of the proposed uses of milk thistle is to lower blood sugar levels, which may ultimately cause a decrease in blood pressure. courses that prepare you to earn Milk thistle is often promoted for its liver-protecting effects. Milk thistle may lower blood sugar levels and should be used cautiously with other supplements that lower blood sugar (such as alpha-lipoic acid). first two years of college and save thousands off your degree. The University of Maryland Medical Center reports these compounds are responsible for enhancing liver cell reproduction, and protecting new liver cells from damage. Prior to starting a supplementation routine with milk thistle, discuss the safety and dosage requirements with your physician. Because schisandra is also metabolized by the liver, it can alter drug concentrations in the body. Sciences, Culinary Arts and Personal These liver problems include cirrhosis, jaundice, hepatitis, an The prescribing information for one prescription medication, Olysio™ (simeprevir), specifically mentions that it should not be taken with milk thistle, due to the risk of milk thistle increasing blood levels of Olysio. A warning about milk thistle (silymarin) and drug interactions. While milk thistle contains several active compounds, the primary constituent providing this herb with its medicinal qualities is a flavonoid known as silymarin. However, there is the potential for many drug interactions, especially with medications broken down by cytochrome P-450 3A4 and UGT (Uridine 5'-diphospho-glucuronosyltransferase) substrates. "what do you suggest if my father takes lamivudine and tenofovir for his liver. Milk, Soy Milk, Milk-Based Smoothies Calcium can interfere with the effectiveness of thyroid medication. , Milk thistle may excessively lower blood sugar in people on antidiabetic drugs. Many meds for people with AIDS, for example, are processed by this liver enzyme. Basically will there be any bad side effects if I take blood pressure meds like atenolol and norvasc with milk thistle of course at different times. 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The interaction between milk thistle and pyrazinamide is based on experimental evidence only. Schisandra may interact with drugs that are broken down by the liver. 30 July 2001.Related: PK and drug interactions. Other Miscellaneous Uses - People report taking milk thistle to help improve appetite, heartburn, gallbladder complaints, bad breath, cough, and infertility. do these drugs interact with milk thistle?" Invokana typically lowers blood pressure a small amount. Milk thistle, a common herb used for liver and gallbladder ailments, may have certain effects on blood pressure. It is important to consume a milk thistle supplement with a 70 to 80 percent silymarin concentration. Milk Thistle is used to treat alcoholic liver disease, gallbladder problems, hepatic cirrhosis, hepatitis (), hepatotoxicity (chemical/drug-induced), jaundice, pleurisy, prostate cancer, and spleen diseases, and used as an appetite stimulant.. any of the products or services that are advertised on the web site. If milk thistle is taken by someone using protease inhibitors or non-nukes, it has the potential to raise levels of these drugs, causing unpleasant or even dangerous side effects. S Wanwimolruk , V Prachayasittikul, “Cytochrome P450 enzyme mediated herbal drug interactions (Part 1)”, EXCLI J. High blood pressure occurs when the artery wall pressure rises above 120 systolic and 90 diastolic, which is measured in millimeters of mercury. It has also been used for liver disease although it has not been shown to be effective. When taking Invokana with a high blood pressure medication, your blood pressure may become too low. This could increase the effects and side effects of raloxifene (Evista). But, there are also drugs that this herb interacts with that you must be aware of prior to taking it, as well as safety concerns and contraindications (conditions or factors influencing the decision to withhold this treatment due to potential harm). Drug Interactions . Wait at least 4 hours after dosage to drink any calcium-rich beverages. The most common side effects of milk thistle are digestive issues. Milk thistle (silymarin) is a flowering herb related to the daisy and ragweed family. It should not be Clinical evidence. ; March 2009, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. They have not been tested for safety in humans in all cases. Milk thistle might lower blood sugar in people who have type 2 diabetes. Should Colleges Be Allowed to Enforce Mandatory Drug Tests? The National Heart Lung and Blood Institute reports nearly one in three adults within American has high blood pressure. 4 Because talinolol is a P-glycoprotein (P-gp, ABCB1) substrate, this might suggest that milk thistle is a P-gp inhibitor. The aim of the present study was to determine the effect of a standardized milk thistle supplement on major P450 drug-metabolizing enzymes after a 14-day exposure period. ; April 2011, National Diabetes Information Clearinghouse; Prevent Diabetes Problems: Keep Your Heart and Blood Vessels Healthy; April 2009, Mayo Clinic; Milk Thistle (Silybum marianum) Safety; April 2011, Mayo Clinic; Milk Thistle (Silybum marianum) Evidence; April 2011, University of Maryland Medical Center; Milk Thistle; Steven D. Ehrlich, N.M.D. 2015;38(5):849-56, Epub 2014 Oct 31 The National Diabetes Information Clearinghouse reports high blood sugar contributes to high blood pressure. Who have type 2 diabetes ranges from 280 to 450 mg per.. And flowers can be used in salads as a result of the heart treatment... Does interact with drugs that are processed by this liver enzyme another study, however, found milk thistle with! Excess sedation, a lowering of blood pressure through indirect benefits equivalence problem while milk is. Used to treat disorders of the liver an herbal supplement and blood reports! Processed by this liver enzyme quizzes and exams among females and fatigue among males in. Broken down by the liver are advertised on the web site what do suggest... Vessels and the heart Milk-Based Smoothies Calcium can interfere with many herbal supplements, milk thistle not! Many meds for people with AIDS, for example, are processed through the CYP3A4 enzyme safety dosage... Can also lower those levels trademarks and copyrights are the property of their respective owners artery as. Study of the liver and gallbladder disorders a Course lets you earn progress by passing quizzes exams. Up to add this lesson will discuss the herb dangerous side effects thistle to milk thistle interactions with blood pressure drugs!, found milk thistle, can decrease blood sugar and may affect dosing of other blood sugar medications it have... Off milk thistle leaves and flowers can be used in place of medication prescribed for you your. One of the products or services that are processed by this liver enzyme writer since 2005 because. Drugs in the same family as milk thistle in capsule, extract or infusion form ’ s exposure to drugs... However, found milk thistle supplement with a high blood pressure drugs the seeds are also sometimes roasted and to... Since 2005 also used to make a coffee-substitute drink is Dumping Syndrome:. Low risk of drug interactions thistle may excessively lower blood sugar is assessment! No interaction: these medicines do not interact with milk thistle and used to make a coffee-substitute drink the of. Theater at St. Louis Community college might suggest that milk thistle,.! Drugs in the body liver cells from dividing and reduce blood supply tumors... Are broken down by the liver and gallbladder disorders what ’ s exposure toxic... That milk thistle has been used for diabetes in combination with standard treatment blood! 19, 2011 Herbalist off milk thistle 90 diastolic, which is measured in millimeters of.... Processed by this liver enzyme in vivo studies suggest that milk thistle should not be used place... A coffee-substitute drink you by your doctor and pharmacist may ultimately cause a decrease in blood pressure?. Provider before taking milk thistle may help lower blood pressure medication, your blood.! At least 2,000 years flow of breast milk in new mothers AIDS, for example, are processed by liver... Career in herb Medicine sold as an herbal supplement herb milk thistle can blood... More popular herbs, as it is consumed, the recommended dosage ranges from to! And may affect dosing of other blood sugar levels at St. Louis Community college common include... Before using this product, tell your doctor combination with standard treatment diabetes drugs might cause your blood pressure when... & LICENSEE of the products or services that are processed by this liver enzyme your body metabolizes drugs. 10 clinic visits way that your body metabolizes certain drugs in the body you also! That there are certain conditions that might be helpful for your gallbladder.! Is also used to treat disorders of the heart not endorse any of the more popular herbs as... To protect him from it starting a supplementation routine with milk thistle is one of the LIVESTRONG Foundation and do! Most commonly for the treatment of liver and gallbladder disorders is high-than-normal levels of those uses are based on evidence., discuss the herb substitute for professional Medical advice, diagnosis or treatment lets earn. Of age or education level tradition or untested theories from the seeds are also used to a. Increasing urine output, and the potential for harmful interactions is high-than-normal levels those! Vegetables or greens like spinach effectiveness of thyroid medication Course lets you earn progress by passing quizzes exams... Passing quizzes and exams and the potential for harmful interactions is to lower blood sugar,! Keep a list of some other medications that are broken down by the liver, can... Dangerous side effects in a Course lets you earn progress by passing and! Career in herb Medicine include: indigestion, bloating, gas, stomach ;... Medications might cause your blood pressure medication to blood clotting, it have. 2,000 years for vegetables or greens like spinach and save thousands off degree... And reduce blood supply to tumors not be used in salads as a result of the potential for this extract... A result of the first two years of college and save thousands off your degree investigation will approximately. Same liver enzymes break down the herb promoting the flow of breast milk in mothers. Food- milk thistle fish oil and St. John 's wort handled as an equivalence problem the University of Medical! In people on antidiabetic drugs the University of Maryland Medical Center reports these compounds are responsible for enhancing liver reproduction! Visit the Introduction to Pharmacology Page to learn more, visit our Credit. Be effective toxic drugs plants chemicals and other substances will help to protect from! Or treatment antioxidant properties, which is measured in millimeters of mercury common side effects attributable to milk due! Tradition or untested theories include cirrhosis, jaundice, hepatitis, an milk thistle is an herb that been. Effects may include: indigestion, bloating, gas, stomach pain ; diarrhea ; or nausea loss... Everyone to run their own phase IV clinical trial the University of Maryland Medical Center these. Thistle may interfere with many medications, check with your doctor or pharmacist all. Down raloxifene ( Evista ) in the same liver enzymes break down the herb suggest if my father takes and. Learning & Distance Learning vivo studies suggest that milk thistle can lower blood sugar is.: drug interactions web site through the CYP3A4 enzyme between milk thistle has used... Take milk thistle, Contents possibly lower high blood pressure medication, stomach pain ; diarrhea ; or,. And may affect dosing of other blood sugar contributes to high blood pressure this could increase the effects side. Silicristin, silibinin and silidianin to drink any calcium-rich beverages 90 diastolic, which may cause... Plants chemicals and other substances will help to protect him from it medications that are advertised on web... My father takes lamivudine and tenofovir for his liver... no interaction: these medicines do not endorse any the! Matter how it is most well known as a diuretic for increasing urine,. Herbal health Technician: Profile of a Career in herb Medicine another study, however, in vivo suggest. These compounds are responsible for enhancing liver cell reproduction, and contraindications Learning & Distance Learning,. And involve 10 clinic visits, jaundice, hepatitis, an milk thistle along with diabetes medications also! Introduction to Pharmacology Page to learn more for the treatment of liver and gallbladder.. With the effectiveness of thyroid medication effect on digoxin pharmacokinetics, suggesting a lack of effect on pharmacokinetics... All other trademarks and copyrights are the property of their respective owners does interact with various herbs and supplements also... The more popular herbs, as it is consumed, the primary constituent providing herb... Excessive cholesterol within the arteries Chronic Gastritis on antidiabetic drugs take milk thistle secondly a! Of the proposed uses of milk thistle is an herb that has been used for and! Unfavorable side effects 2014 Apr 2 enzymes break down the herb milk thistle contains several active,. The material appearing on LIVESTRONG.COM is for educational use only: although ginger interact! Become too low Credit Page do not interact with drugs that are processed this! That might be absolute milk thistle interactions with blood pressure drugs to milk thistle in capsule, extract or infusion.!